体重不一致双胎早产儿的体重与新生儿并发症的相关分析

doi:10.12372/jcp.2025.24e1140

Abstract

Abstract:

Objective To select inconsistent birth weight twins who were preterm, and evaluate the relationship between birth weight and neonatal complications. Methods Twins with inconsistent birth weights who were admitted to the neonatal intensive care unit (NICU) in three hospitals in Xinxiang City from January 2018 to May 2024 were selected, totaling 112 pairs. The twins with inconsistent birth weights were divided into a higher birth weight group (n=112) and a lower birth weight group (n=112). The incidence of complications such as neonatal respiratory distress syndrome (NRDS) and respiratory support in both groups were compared. Results The lower birth weight group had more small-for-gestational-age (SGA) infants compared to the higher birth weight group, with a statistically significant difference (P<0.001). The incidence of NRDS in the higher birth weight group was higher than in the lower birth weight group (P<0.05), while the incidence of bronchopulmonary dysplasia (BPD) was lower in the higher birth weight group compared to the lower birth weight group (P<0.05). Conclusion In twins with inconsistent birth weights, those with higher birth weights are more likely to develop NRDS, while those with lower birth weights are more likely to develop BPD.

Key words: twins, birth weight discordance, neonatal respiratory distress syndrome, bronchopulmonary dysplasia, preterm infants

LI Yizhan, TANG Chenghe, ZHANG Mingxia, ZHANG Youle, ZHANG Weixing, YUAN Li. Correlation analysis of birth weight and neonatal complications in preterm twins with discordant birth weight[J].Journal of Clinical Pediatrics, 2025, 43(5): 329-333.

Figures/Tables 2

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Table 2

References 23

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项目	体重大组(n=112)	体重小组(n=112)	统计量	P
性别[n(%)]
男	65(58.04%)	55(49.11%)	χ²=2.70	0.099
女	47(41.96%)	57(50.89%)	χ²=2.70	0.099
出生体重($\bar{x}±s$)/g	2277.0±478.5	1 772.4±434.7	t=17.51	<0.001
双胎之先分娩者[n(%)]	65(58.04%)	47(41.96%)	χ²=2.89	0.108
1 min Apgar评分≤7分[n(%)]	17（15.18%）	19（16.96%）	χ²=0.06	0.804
5 min Apgar评分≤7分[n(%)]	10（8.93%）	8（7.14%）	χ²=0.13	0.727
脐动脉血pH值[M(P₂₅~P₇₅)]	7.31（7.27~7.35）	7.32（7.28~7.35）	Z=0.65	0.516
SGA[n(%)]	6（5.36%）	47（41.96%）	χ²=39.09	<0.001

项目	体重大组(n=112)	体重小组(n=112)	统计量	P
新生儿窒息	20(17.86)	20(17.86)	χ²=0.06	1.000
NRDS	55(49.11)	40(35.71)	χ²=6.32	0.011
BPD	4(3.57)	13(11.61)	χ²=7.11	0.004
肺出血	1(0.89)	2(1.79)	χ²=0.00	1.000
新生儿肺炎	74(66.07)	75(66.96)	χ²=0.00	1.000
PPHN	1(0.89)	2(1.79)	χ²=0.00	1.000
NEC	4(3.57)	5(4.46)	χ²=0.00	1.000
PDA	29(25.89)	24(21.43)	χ²=2.28	0.125
ROP	3(2.68)	2(1.79)	χ²=0.00	1.000
败血症	23(20.54)	24(21.43)	χ²=0.00	1.000
贫血	40(35.71)	48(42.86)	χ²=1.44	0.229
使用PS	33(29.46)	24(21.43)	χ²=3.37	0.064
机械通气	8(7.14)	4(3.57)	χ²=1.50	0.219
CPAP	79(70.54)	79(70.54)	χ²=0.05	1.000
鼻导管吸氧	69(61.61)	69(61.61)	χ²=0.05	1.000

Correlation analysis of birth weight and neonatal complications in preterm twins with discordant birth weight

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