Journal of Clinical Pediatrics ›› 2023, Vol. 41 ›› Issue (3): 229-234.doi: 10.12372/jcp.2023.22e0943

• Literature Review • Previous Articles     Next Articles

Research progress on environmental factors and congenital heart disease

Reviewer: RUAN Xuehua, Reviser: SUN Jing, SUN Kun   

  1. Department of Pediatric Cardiology, Xinhua Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200092, China
  • Received:2022-07-13 Online:2023-03-15 Published:2023-03-10

Abstract:

Congenital heart disease (CHD) is a common birth defect, and its incidence is on the rise in China. At present, congenital heart disease is generally believed to be the result of the combined effect of genetic factors and environmental factors, but the specific etiology and pathogenesis are still not clear. More and more studies focus on the impact of parental environmental exposure before and during pregnancy on congenital heart disease. This article summarizes the environmental factors related to CHD in recent years, summarizes the potential influencing mechanism, and provides reference for preventing and controlling the occurrence of CHD.

Key words: congenital heart disease, environmental factor, mechanism