临床儿科杂志 ›› 2019, Vol. 37 ›› Issue (10): 765-.doi: 10.3969/j.issn.1000-3606.2019.10.011

• 综合报道 • 上一篇    下一篇

儿童支原体肺炎合并肺栓塞1 例报告

秦嫣然 1, 王华华 2, 王燕 3, 张伟 3, 何玲 4, 刘成军 1   

  1. 1.重庆医科大学附属儿童医院重症医学科 儿科学重庆市重点实验室 儿童发育疾病研究教育部重点 实验室 国家儿童健康与疾病临床医学研究中心(重庆) 儿童发育重大疾病国家国际科技合作基地 (重庆 400014);2.重庆市职业病防治院儿科(重庆 400080);3.重庆医科大学附属永川医院儿科 (重庆 402160);4.重庆医科大学附属儿童医院放射科(重庆 400014)
  • 发布日期:2020-01-22
  • 通讯作者: 刘成军 电子信箱:liucwd@163.com

Mycoplasma pneumoniae pneumonia complicated with pulmonary embolism in children: a case report

 QIN Yanran1, WANG Huahua2, WANG Yan3, ZHANG Wei3, HE Ling4, LIU Chengjun1   

  1. 1. Department of PICU, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders (Chongqing), China International Science and Technology Cooperation base of Child derelopment and Critical Disorders, Children’s Hospital of Chongqing Medical University, Chongqing 400014, China; 2. Department of Pediatrics, Occupational Disease Prevention Hosptial, Chongqing 400080, China; 3. Department of Pediatrics, Yongchuan Hospital of Chongqing Medical University, Chongqing 402160, China; 4. Department of Radiology, Children’s Hospital of Chongqing Medical University, Chongqing 400014, China
  • Published:2020-01-22

摘要: 目的 探讨儿童支原体肺炎合并肺栓塞的临床诊断和治疗。方法 回顾分析1例支原体肺炎合并肺栓塞患 儿的临床资料。结果 女性患儿,10岁,以咳嗽、发热、气促为主要表现。肺炎支原体抗体滴度1:320,抗心磷脂抗体IgM 阳性,D-二聚体42.4 μg/mL。CT肺动脉造影提示肺动脉栓塞。确诊为支原体肺炎、肺栓塞后,予以阿奇霉素抗感染、华法 林及低分子肝素钙抗凝、改善循环、雾化祛痰等治疗。经3个月抗凝治疗后,患儿肺栓塞治愈。结论 对于呼吸困难、胸痛, 并伴有抗心磷脂抗体阳性、D-二聚体升高等的支原体肺炎患儿应考虑肺栓塞可能,及时完善肺动脉CT造影以明确诊断。

关键词: 支原体肺炎; 肺栓塞; 抗磷脂抗体; CT肺动脉造影

Abstract:  Objective To explore the clinical diagnosis and treatment of Mycoplasma pneumoniae pneumonia complicated with pulmonary embolism in children. Method The clinical data of Mycoplasma pneumoniae pneumonia complicated with pulmonary embolism in a child were retrospectively analyzed. Results A 10-year-old female patient presented with cough, fever and tachypnea. The titer of Mycoplasma pneumoniae antibody was 1:320, the anti-cardiolipin antibody IgM was positive, and the D-dimer level was 42.4 μg/mL. CT pulmonary angiography suggested a pulmonary embolism. After the diagnosis of mycoplasma pneumonia and pulmonary embolism, azithromycin was given for anti-infection, warfarin and low molecular weight heparin calcium were given for anticoagulation and circulation improvement, atomization technique was given to eliminate phlegm. After 3 months of anticoagulation therapy, pulmonary embolism was cured. Conclusions If the child with Mycoplasma pneumoniae pneumonia has dyspnea and chest pain accompanied by positive anti-cardiolipin antibody and increased D-dimer, pulmonary embolism should be considered and pulmonary artery CT angiography should be timely performed to make a clear diagnosis.

Key words:  Mycoplasma pneumoniae pneumonia; pulmonary embolism; antiphospholipid antibody; CT pulmonary angiography