临床儿科杂志 ›› 2014, Vol. 32 ›› Issue (1): 30-32.

• 专家笔谈 • 上一篇    下一篇

健康婴儿心率减速力和心率变异性的变化及其相关性

易兰芬文红霞邱梅   

  1. 武汉市儿童医院心电图室 (湖北武汉 430016)
  • 收稿日期:2014-01-15 出版日期:2014-01-15 发布日期:2014-01-15

Study on changes in heart rate deceleration capacity and variability and their correlation in healthy infants YI Lanfen, WEN Hongxia, QIU Mei (Department of Electrocardiogram, Wuhan Children's Hospital, Wuhan 430016, Hubei, China)

  • Received:2014-01-15 Online:2014-01-15 Published:2014-01-15

摘要:

 目的 观察健康婴儿的心率减速力(DC)、心率加速力(AC)和心率变异性(HRV)的变化及其相关性。 方法 82例健康婴儿接受24 h动态心电图检查,按月龄不同分为小婴儿组(<6个月)和大婴儿组(6~12个月)。计算机自动测定其24 h的DC、AC及HRV时域指标(SDNN、SDANN、RMSSD、PNN50)与频域指标(LF、HF);比较两组婴儿的DC、AC及HRV各项指标,并分析DC、AC与HRV各项指标之间的相关性。 结果 大婴儿组的DC为(3.96±1.53)ms 明显高于小婴儿组的(3.20±1.44)ms,而AC为(-3.84±1.10)ms明显低于小婴儿组的(-3.11±0.95)ms,差异有统计学意义(P均<0.05)。24 h DC与心率呈显著负相关(r=-0.56,P=0.000),与SDNN、SDANN、RMSSD、PNN50、LF和HF之间呈显著正相关(r=0.25~0.75,P均<0.05);24 h的AC值与心率呈显著正相关(r=0.78,P=0.000),与SDNN、SDANN、RMSSD、PNN50、LF和HF之间呈显著负相关(r=-0.88~-0.56,P均<0.01)。 结论 婴儿期的DC与HRV多项指标随月龄增加而增大,AC随月龄增加而减小;DC、AC与心率及HRV各项指标密切相关。

Abstract:  Objectives To observe the changes in heart rate deceleration capacity (DC), acceleration capacity (AC) and heat rate variability (HRV) and their correlation in healthy infants. Methods A total of 82 healthy infants who were divided into early infant group (<6 months) and late infant group (6-12 months) received 24 h dynamic electrocardiogram examination. The DC and AC value, time domain indices (SDNN, SDANN, RMSSD, PNN50) and frequency domain indices (LF, HF) of HRV were measured automatically by computer and compared between two infant groups. Moreover, the association of DC, AC value and HRV indices was analyzed. Results In late infant group, the DC value was (3.96±1.53) ms, higher than that in early infant group (3.20±1.44) ms, while the AC value was (-3.84±1.10) ms, lower than that in early infant group (-3.11±0.95) ms, and the differences were significant (P<0.05). The DC value derived from 24-hour Holter recordings was negatively related to heart rate (r=-0.56, P=0.000), while positively related to SDNN, SDANN, RMSSD, PNN50, LF and HF (r=0.25~0.75, P<0.05). The AC value derived from 24-hour Holter recordings was positively related to heart rate (r=0.78, P=0.000), while negatively related to SDNN, SDANN, RMSSD, PNN50, LF and HF (r=-0.88~-0.56, P<0.01). Conclusions The DC value and HRV indices are increased with age while AC value was decreased with age. The DC and AC value are closely associated with heart rate and HRV indices.