临床儿科杂志 ›› 2018, Vol. 36 ›› Issue (8): 621-.doi: 10.3969/j.issn.1000-3606.2018.08.014

• 综合报道 • 上一篇    下一篇

注意缺陷多动障碍伴孤独症特征儿童社交相关行为问题及 执行功能研究#br#

季忆婷 1,3, 范云 3, 张婷 3, 冯蔚 3, 舒艳 3, 陈亮亮 3, 朱涛 3, 李斐 2,3, 刘欣 3   

  1. 1.上海交通大学医学院附属上海儿童医学中心发育行为儿保科(上海 200127);2.上海交通大学 医学院附属新华医院发育行为儿保科(上海 200092);3.环境与儿童健康教育部重点实验室、 上海市重点实验室(上海 200092)
  • 收稿日期:2018-08-15 出版日期:2018-08-15 发布日期:2018-08-15
  • 通讯作者: 刘欣,李斐 E-mail:liuxin_525l@163.com,feili@shsmu.edu.cn
  • 基金资助:
    国家自然科学基金(No.81571031, No.81761128035, No.81781220701);上海市科委优秀学术带头人计划 (No.17XD1403200);上海市卫生计生系统项目(No.2017ZZ02026, No.2017EKHWYX-02, No.GDEK201709, No.2018BR33);上海市教委高原高峰计划(研究型医师项目,No.20152234);上海市申康三年行动计划项目 (No.16CR2025B )

The behavior characteristics and executive functions of ADHD children with autistic traits

 JI Yiting1,3, FAN Yun3, ZHANG Ting3, FENG Wei3, SHU Yan3, CHEN Liangliang3, ZHU Tao3, LI Fei2,3, LIU Xin3   

  1. 1.Department of Developmental Behavioral Pediatrics, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China; 2.Child Health Care Department, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200029, China 3.MOE-Shanghai Key Laboratory of Children’s Environmental Health, Shanghai 200029, China
  • Received:2018-08-15 Published:2018-08-15 Online:2018-08-15

摘要: 目的 比较注意缺陷多动障碍(ADHD)伴孤独症特征(ATs)儿童和一般ADHD儿童临床特征及执行功能 的差异。方法 2015年12月至2017年1月收集ADHD患儿临床资料,根据其社交反应量表(SRS)得分,选择ADHD伴 ATs(ADHD-ATs组)80例和一般ADHD(ADHD组)95例;比较两组患儿SNAP-Ⅳ评定量表、Conners父母用症状问卷及 执行功能行为评定量表(BRIEF)的评估结果。结果 两组患儿的年龄、性别及智商差异无统计学意义(P>0.05)。 与 ADHD组比较,ADHD-ATs组SNAP-Ⅳ量表中多动核心症状、Conners问卷中的行为问题更明显,差异均有统计学意 义(P<0.05)。“ 冷”、“ 热”执行功能比较中,相较ADHD组,ADHD-ATs组的BRIEF得分均更高,心理理论(口语)得分 和总分更低,差异均有统计学意义(P<0.05)。 回归分析显示,“ 冷”、“ 热”执行功能与患儿社交行为问题有显著相关性 [BRIEF行为管理指数:β =-1.17, P<0.01,95%CI:- 2.00~-0.34;心理理论(口语):β =0.72, P<0.001,95%CI: 0.51~0.93]。结论 ADHD-ATs患儿较一般ADHD患儿的多动核心症状更为明显,执行功能上受损也更为严重。

Abstract: Objective To assess behavior characteristics and social functioning of children with attention-deficit/ hyperactivity disorder (ADHD)-autistic traits (ATs) and ADHD control (without ATs), and to explore the associations between the executive functions and the impairments of behavior. Method A total of 175 ADHD children diagnosed in the Departmen of Behavior Pediatrics in Shanghai Children's Medical Center and Xinhua Hospital were selected and divided into ADHD with autism traits (ADHD-ATs) group (n=80) and ADHD without autism traits (ADHD) group (n=95) by the scores of social response scale. All participants completed IQ test and questionnaires such as SNAP-Ⅳ, Conners Parent Symptom Questionnaire and Behavior Rating Inventory of Executive Function.  Results  There was no significant difference between the two groups in age, gender and IQ (P>0.05). ADHD-ATs children behaved worse in hyperactivity/impulsive behavior (P<0.05), worse impaired in theory of mind than ADHD children (P<0.05). Further regression analysis found that the impact of cold and hot executive functions had a significant relationship with social behavior problems (behavior management index: β =-1.17, P <0.05, 95% CI: -2.00~-0.34; theory of mind (oral): β =0.72, P<0.05, 95% CI:0.51~0.93). Conclusions Children with ADHD-ATs had more serious symptoms than children with ADHD, and with impaired cold and hot executive functions.
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