早产儿血流动力学显著的动脉导管未闭危险因素和预测指标研究进展

doi:10.12372/jcp.2023.22e0327

摘要/Abstract

摘要：

动脉导管未闭（PDA）是早产儿较为常见的并发症，当其进展为血流动力学显著的PDA（hsPDA）时可严重影响新生儿预后。近年研究发现一些围生期因素、血小板相关参数、脑钠肽、超声指标等能够预测hsPDA的发生且形成了人工智能预测模型。但一些预测指标仍有争议，需要进一步研究，以构建出灵敏度、准确度高且应用方便的预测模型，以便对高风险患儿进行预防性治疗，改善早产儿预后。

关键词: 动脉导管未闭, 危险因素, 预测指标, 早产儿

Abstract:

Objective Patent ductus arteriosus (PDA) is a common complication in premature infants. When it progresses to PDA with significant hemodynamics (hsPDA), it can seriously affect neonatal outcomes. Recent studies have found that some perinatal factors, platelet-related parameters, brain natriuretic peptide and ultrasound indicators can predict the occurrence of hsPDA and form an artificial intelligence prediction model. However, some predictors are still controversial, and further research is needed to build a sensitive, accurate and easy-to-use prediction model for targeted treatment of high-risk children to improve the prognosis of premature babies.

Key words: patent ductus arteriosus, risk factor, predictor, premature infant

赵彩艳, 孙玄, 陈玲. 早产儿血流动力学显著的动脉导管未闭危险因素和预测指标研究进展[J]. 临床儿科杂志, 2023, 41(6): 475-479.

ZHAO Caiyan, SUN Xuan, CHEN Ling. Advances in studies on risk factors and predictors of patent hemodynamically significant ductus arteriosus in premature infants[J]. Journal of Clinical Pediatrics, 2023, 41(6): 475-479.

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