Journal of Clinical Pediatrics ›› 2023, Vol. 41 ›› Issue (9): 708-714.doi: 10.12372/jcp.2023.22e0604

• Literature Review • Previous Articles     Next Articles

Research progress on early screening and diagnosis of Crohn's disease in children

Reviewer: WANG Chenhui, Reviser: YANG Hui   

  1. Degestive Department, Children's Hospital Affiliated to Nanjing Medical University, Nanjing 210008, Jiangsu, China
  • Received:2022-04-27 Online:2023-09-15 Published:2023-09-05


Crohn's disease (CD) is a chronic nonspecific gastrointestinal inflammatory disease. The onset of CD in children is insidious, the clinical manifestations are lack of specificity, and early diagnosis is difficult, which leads to the increased complications, surgical rates and disability rates. Early screening and diagnosis, timely intervention can improve the therapeutic effect and prognosis of children, and improve the life quality of children. This article reviews the progress of early screening and diagnosis of CD in children.

Key words: Crohn's disease, serum marker, intestinal microorganisms, metabonomics, child