Journal of Clinical Pediatrics ›› 2023, Vol. 41 ›› Issue (12): 903-907.doi: 10.12372/jcp.2023.22e1553
• Urinary System Disease • Previous Articles Next Articles
WANG Meiqiu1, HE Xu2, WANG Ren2, JIA Lili2, GAO Chunlin2, XIA Zhengkun1()
Received:
2022-11-22
Online:
2023-12-15
Published:
2023-12-04
WANG Meiqiu, HE Xu, WANG Ren, JIA Lili, GAO Chunlin, XIA Zhengkun. Risk factors of poor renal prognosis in children with Henoch-Schönlein purpura nephritis[J].Journal of Clinical Pediatrics, 2023, 41(12): 903-907.
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项 目 | 预后良好组(n=445) | 预后不良组(n=31) | 统计量 | P |
---|---|---|---|---|
男性[n(%)] | 258(58.0) | 20(60.5) | χ2=0.51 | 0.475 |
发病年龄[M(P25~P75)]/岁 | 10.5(8.0~13.2) | 12.6(11.5~13.3) | Z=2.29 | 0.022 |
皮疹到肾脏受累时间[M(P25~P75)]/d | 11.0(0.0~31.0) | 0.0(0.0~31.0) | Z=1.02 | 0.307 |
肾脏受累到肾穿时间[M(P25~P75)]/d | 36.0(19.0~101.5) | 86.0(37.0~531.0) | Z=3.22 | 0.001 |
肉眼血尿[n(%)] | 67(15.1) | 4(12.9) | - | 1.0001) |
腹痛[n(%)] | 185(41.6) | 12(38.7) | χ2=0.10 | 0.754 |
关节痛[n(%)] | 153(34.4) | 7(22.6) | χ2=1.81 | 0.179 |
随访时间[M(P25~P75)]/月 | 33.8(20.9~53.8) | 34.5(21.2~89.8) | Z=1.07 | 0.284 |
贫血[n(%)] | 77(17.3) | 7(22.6) | χ2=0.56 | 0.456 |
低血清白蛋白[n(%)] | 19(4.3) | 2(6.5) | - | 0.6391) |
高胆固醇[n(%)] | 132(29.7) | 15(48.4) | χ2=4.76 | 0.029 |
高尿酸血症[n(%)] | 51(11.5) | 10(32.3) | - | 0.0031) |
eGFR<90 mL/(min·1.73 m2)[n(%)] | 9(2.0) | 4(12.9) | - | 0.0071) |
大量蛋白尿[n(%)] | 50(11.2) | 9(29.0) | - | 0.0081) |
高尿NAG酶[n(%)] | 293(65.8) | 24(77.4) | χ2=1.75 | 0.186 |
高尿RBP[n(%)] | 68(15.3) | 13(41.9) | χ2=14.58 | <0.001 |
高尿C3[n(%)] | 158(35.5) | 11(35.5) | χ2=0.00 | 0.998 |
高尿α2-M[n(%)] | 57(12.8) | 7(22.6) | - | 0.1661) |
RAS阻滞剂[n(%)] | 177(39.8) | 12(38.7) | χ2=0.01 | 0.907 |
应用泼尼松[n(%)] | 401(90.1) | 29(93.6) | - | 0.7561) |
甲泼尼龙冲击治疗[n(%)] | 158(35.5) | 12(38.7) | χ2=0.13 | 0.719 |
应用免疫抑制剂[n(%)] | 175(39.3) | 8(25.8) | χ2=2.24 | 0.135 |
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