Abstract:

Asthma is one of the most common chronic respiratory diseases, affecting all age group. Its prevalence and social healthcare costs are increasing every year. The results of numerous studies in recent years have conclusively demonstrated the role of lipid molecules as powerful signaling molecules that regulate a variety of cellular biological processes. By regulating different cells in the airways of asthma patients, they influence the occurrence and development of the disease. Therefore, this article summarizes the potential metabolic biomarkers in asthma, and explores the mechanisms of lipid metabolism in asthma pathogenesis on different cells to provide ideas for personalized asthma treatment from the lipidomics and asthma studies that have been developed in recent years.

Key words: asthma, lipid metabolism, lipidomics, fatty acids, immune cell