Journal of Clinical Pediatrics ›› 2025, Vol. 43 ›› Issue (3): 226-232.doi: 10.12372/jcp.2025.24e0499

• Literature Review • Previous Articles     Next Articles

Application of precision therapy in pediatric inflammatory bowel disease

JIA Shuangzhen, KONG Yan, LIU Qian-chao, ZHU Ailin, WU Jie()   

  1. Department of Gastroenterology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China
  • Received:2024-05-16 Accepted:2024-08-12 Published:2025-03-15 Online:2025-02-27

Abstract:

Pediatric inflammatory bowel disease (IBD) is a chronic, recurrent inflammatory condition of the intestines with unknown etiology and complex pathogenesis, posing significant challenges in diagnosis and treatment. IBD severely impacts the growth and development of affected children, diminishes their quality of life, and may negatively influence their psychological and social behavior, imposing a substantial economic burden on society. In recent years, the incidence of pediatric IBD in China has been on the rise, drawing significant attention from pediatricians. Establishing a new model of precision therapy for pediatric IBD has become a goal for pediatricians and scholars worldwide. Precision medicine has proven effective in early screening and diagnosis of cancers and neonatal genetic diseases, providing new methods and perspectives for the treatment of pediatric IBD. This paper reviews the current application of precision therapy in pediatric IBD, elucidating its role in the treatment of pediatric IBD.

Key words: inflammatory bowel disease, precision therapy, treatment strategies, child