Abstract:

Bronchopulmonary dysplasia (BPD) is a common complication in preterm infants with gestational age ≤32 weeks, which has long-term adverse effects on respiratory and nervous system development of newborns. BPD is caused by the combined action of many factors and its etiology is complex. The diversity of respiratory tract microecology and its abnormal evolution mode will increase the risk of BPD. The microecology of the respiratory tract is affected by many factors, and its imbalance can increase the risk of developing various systemic diseases later in life. This paper reviews the influencing factors of respiratory tract microecology and their significance and research progress in BPD, aiming to strengthen the understanding of their relationship and provide a new entry point for the prevention and treatment of BPD.

Key words: bronchopulmonary dysplasia, chronic lung disease, microecology, premature infant