基于母乳蛋白组成优化婴儿配方奶粉蛋白质组分的意义、进展与挑战

doi:10.12372/jcp.2025.25e0684

摘要/Abstract

摘要：

母乳是婴儿最佳食物。母乳蛋白质为婴儿提供完善的必需氨基酸以及多种活性功能，支持免疫、神经发育。婴儿配方奶粉作为母乳代用品，终极目标是接近母乳喂养效果。目前婴儿配方奶粉蛋白质优化的策略包括减少总蛋白质含量、添加母乳中证实有活性功能的蛋白质、调整蛋白质结构更接近母乳。但是目前优化后婴儿配方奶粉蛋白质仍与母乳有差距，还需进一步深入研究。

关键词: 母乳, 蛋白质, 婴儿配方奶粉

Abstract:

Human milk is the optimal food for infants. Proteins in human milk provide essential amino acid for growth, and multiple bioactivities for immunity and neurodevelopment. As a breastfeeding substitute, the ultimate goal of infant formula modification is a feeding outcome similar to breast feeding. The strategies to optimize proteins in infant formula including: lower protein content, addition of validated human milk bioactive proteins, adjustment of protein structure based on human milk. Although efforts have been made, there is still a huge gap between human milk and infant formula which need further research.

Key words: human milk, protein, infant formula

中图分类号:

蒋卓勤. 基于母乳蛋白组成优化婴儿配方奶粉蛋白质组分的意义、进展与挑战[J]. 临床儿科杂志, 2025, 43(8): 569-574.

JIANG Zhuoqin. The significance, progress and challenges of optimizing the protein composition of infant formula based on human breast milk[J]. Journal of Clinical Pediatrics, 2025, 43(8): 569-574.

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