Abstract: Objective　To study the clinical feature, treatment and outcome of newborns with paroxysmal supraventricular tachycardia (PSVT). Methods　A retrospective study of the clinical data from 37 cases collected from January 2005 to December 2014 was performed. Based on whether there was a ventricle pre-excitation performance of the electrocardiogram, the cases were divided into concealed pathway group and Wolff–Parkinson–White syndrome (WPW) group, with further comparasion of the clinical feature, treatment and prognosis between two groups. Results　In 37 cases of newborn PSVT, 28 cases were concealed pathway and 9 cases were WPW syndrome. The gender, gestational age, birth weight, onset age,  fetal original, heart failure, and treatment between the two groups were of no significant differences. The average onset heart rate was significantly different between the two groups (P=0.004). The length of hospital stay and recurrent rate were of no significant differences between the two groups (P>0.05). Conclusion　PSVT is the most important arrhythmia in newborns. There are no obvious differences between the concealed pathway group and WPW syndrome group regarding to the clinical feature, treatment and the prognosis. The heart rate was faster in the WPW syndrome group than that in the concealed pathway group.