关键词: 体外膜氧合, 急性肾损伤, 肾替代治疗, 儿童

Abstract:

Extracorporeal membrane oxygenation (ECMO), as a salvage treatment for severe cardiopulmonary failure, has been widely applied in pediatric patients with severe diseases. Although the survival rate of children is gradually improved after the use of this technique, there are still some complications, such as acute kidney injury, systemic infection, hemorrhage and thrombosis. Studies have shown that acute kidney injury and fluid overload can significantly increase the mortality and prolong the running time of ECMO in children. Therefore, renal replacement therapy is increasingly used for the management of fluid overload and acute kidney injury in patients with ECMO. This article reviewed the strategies of ECMO combined with renal replacement therapy in children, and discussed the incidence and risk factors of acute kidney injury, timing of renal replacement therapy, management strategy of renal replacement therapy, prognosis, and advantages and disadvantages of different renal replacement therapy strategies.

Key words: extracorporeal membrane oxygenation, acute kidney injury, renal replacement therapy, child