临床儿科杂志 ›› 2022, Vol. 40 ›› Issue (12): 950-955.doi: 10.12372/jcp.2022.21e1630

• 文献综述 • 上一篇    下一篇

儿童气道黏液高分泌研究进展

夏莹 综述, 罗健 审校   

  1. 重庆医科大学附属儿童医院呼吸科(重庆 400014)
  • 收稿日期:2021-11-23 出版日期:2022-12-15 发布日期:2022-12-06

Research progress of airway mucus hypersecretion in children

Reviewer: XIA Ying, Reviser: LUO Jian   

  1. Respiratory Department, Children’s Hospital of Chongqing Medical University, Chongqing 400014, China
  • Received:2021-11-23 Online:2022-12-15 Published:2022-12-06

摘要:

气道黏液是人体呼吸系统防御屏障的重要组成部分,病理状态下,过量的黏液分泌将阻塞气道,引起通气功能障碍,降低黏液纤毛清除功能和局部防御功能。儿童常见气道黏液高分泌疾病与成人有很大不同。对于气道黏液高分泌的评估仍在探索中,其治疗方案以减少黏液产生及促进黏液排出为核心。

关键词: 气道黏液高分泌, 机制, 评估, 儿童

Abstract:

Airway mucus is an important part of the human respiratory system's defense barrier. Under pathological conditions, excessive mucus secretion will block the airway, cause ventilatory dysfunction, and reduce mucociliary clearance and local defense functions. The common airway mucus hypersecretion disease in children is very different from that in adults. The assessment of airway mucus hypersecretion is still under exploration, and the core of its treatment is to reduce mucus production and promote mucus excretion.

Key words: airway mucus hypersecretion, mechanism, assessment, child