Journal of Clinical Pediatrics ›› 2026, Vol. 44 ›› Issue (3): 258-263.doi: 10.12372/jcp.2026.25e0251

• Literature Review • Previous Articles     Next Articles

Research progress on comorbidity of attention deficit hyperactivity disorder and mood disorders

LU Dingjie, WANG Yu()   

  1. Department of Rehabilitaion of Child Health Care Medical Division, Shanghai Children′s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200062, China
  • Received:2025-03-17 Accepted:2025-05-20 Published:2026-03-15 Online:2026-03-06

Abstract:

Attention deficit hyperactivity disorder (ADHD) is a chronic neurodevelopmental disorder defined by developmentally inappropriate inattention and/or hyperactivity-impulsivity that impairs daily functioning. Mood disorders are highly prevalent comorbidities in ADHD, exacerbating treatment complexity and exerting adverse effects on core symptom severity and long-term prognosis. This review synthesizes the latest research advances in the epidemiology, pathophysiological mechanisms, assessment-diagnostic strategies, and therapeutic interventions for ADHD comorbid with mood disorders, aiming to provide an evidence-based theoretical foundation for comprehensive clinical diagnosis and integrated management.

Key words: attention deficit hyperactivity disorder, mood disorders, child

CLC Number: 

  • R72