Abstract:

The incidence of acute pancreatitis (AP) in children has shown a yearly increasing trend. Currently, standardized and definitive diagnosis and treatment protocols for severe acute necrotizing pancreatitis in children are lacking, and clinical practice often relies on adapting adult guidelines. Continuous regional arterial infusion of medication has been applied in the treatment of early-stage acute necrotizing pancreatitis in adults. However, the etiology, pathophysiological processes, and pharmacokinetics of AP differ in children compared to adults, with certain individual variations also present. Consequently, reports on its application specifically in children with AP are scarce. This article presents a case of severe acute necrotizing pancreatitis in a child treated via continuous regional arterial infusion, where medication was administered to a specified site through an indwelling catheter. Furthermore, the applicability of continuous regional arterial infusion therapy in pediatric AP is discussed, aiming to contribute to advancements in the diagnosis and management of AP in children.

Key words: severe acute necrotizing pancreatitis, continuous regional arterial infusion, child